http://www.nature.com/nprot/journal/v10/n10/full/nprot.2015.088.html

There is a protocol for conditioned media in here. Good luck!

Thanks

 This paper is a very detailed Nat Protocol on preparing organoid culture media 

http://www.nature.com/nprot/journal/v8/n12/abs/nprot.2013.153.html

I have used it and it works well. Best luck!

I addition to my previous answer, check this paper as well. Hope it helps.

https://www.ncbi.nlm.nih.gov/pubmed/30548444

Generation of Pancreatic Ductal Organoids and Whole-Mount Immunostaining of Intact Organoids.

I am learning to culture organoids. Many thanks for the updating information.