CNV= Copy Number Variation? If it is.

Try Breakdancer, Delly, Pindel each have different algorithms and can complement each other.

Hello Rudy,

i added a review Paper with an general method overview and a paper of ConVaDing, wich performs quite well (for a CNV tool). You are set for a long journey.

Good luck for your research

Article Whole-Genome CNV Analysis: Advances in Computational Approaches

Article CoNVaDING: Single exon variation detection in targeted NGS data

Hi,

I already test several tool on a panel of 300 genes and with positive control. And ExomeDepth gave me the best results. It is a R package, easy to use.

Hoping this could help you