How can I measure MMP-1 protein activity or protein level from liver tissue?

Instead of checking only the mRNA level, I want to check the active protein level of MMP-1 in Liver tissue from mice. How can I do that?

03 March 2021 1,763 2 View

Binary Logistic Generalized Linear Mixed model in SPSS. Is it doable?

I want to analyses the proportion of swimming sperm of three species of fish in two salinities. To analyse the proportion of swimming sperm in a Generalized Linear Model, I would use a Binary...

03 March 2021 2,297 3 View

Looking for Materials with high thermal expansion coefficient and high temperature resistance?

03 March 2021 8,272 1 View

Guidelines for survey (question type) analysis?

Hi. Please tell me what guidelines should i need to follow for questionaries' type research work in India. It is not hospital based work, we are conduction basic institutional based qualitative...

03 March 2021 2,037 3 View

What are the values needed for gabor filter's parameter for cifar10 data?

Hi, I implemented a code to gabor filter cifar10 data but the images after being filtered and stacked are not clear like the original images. I think the problem is in the way I am using the...

03 March 2021 6,317 1 View

Can we block unwanted images during the x-ray prediction?

i am try to classify the x-ray images. During classification , can i block unwanted images (except x-ray image).

03 March 2021 7,100 1 View

No title

03 March 2021 5,360 2 View

What techniques can I use to determine the miscibility of polymer blends?

The term miscibility refers to the single-phase state in thermodynamics. I do not mean the compatibility of different components. To determine the miscibility I know several techniques such as...

03 March 2021 4,107 4 View

Sample dilution for quantitative analysis using ELISA?

If the detection range is in ng/ml but the reference range is in ug/ml for a molecule or protein in serum or plasma .how to dilute and what is the initial volume to be taken for quantitative analysis

02 March 2021 7,670 3 View

The procedure compute?

02 March 2021 5,204 3 View

Can cetuximab recognize mouse EGFR?

I was looking for an antibody that can block the ligand binding domain of mouse EGFR. Can I use Cetuximab or is it exclusively human-specific?

05 June 2018 846 6 View

Cetuximab Resistant PDx models?

Looking for a CRO/academic collaboration who has cetuximab resistant HNSCC/CRC pdx models. Anybody has these models?

02 March 2018 3,158 1 View

How the reaction of an Antibody with Trauts Reagent to create -SH groups can be made succesfull ?

Hello Everyone, I am trying to create -SH groups in cetuximab antibody by reacting it with Traut's reagent. I followed the procedure given by the protocols of Thermo...

31 December 2016 2,080 16 View

Does anyone have an idea for syngeneic tumour models for testing human tumour targeting Ab (e.g. Cetuximab) in immune competent mice ?

Hi, I am looking for syngenic tumor models for evaluating human-specific tumour targeting Ab in immune competent mice. More specifically, I am looking for models expressing either huHER2, huEGFR...

11 December 2015 398 2 View

Any advice on handling & storing antibodies made for infusion?

08 September 2015 3,277 7 View

The best combined chemotherapy regimen for treatment of solid tumors??

11 December 2014 5,325 4 View

Does anyone know how to bind Cetuximab with gold nanorods?

I have started to work with GNR and I need to coat them with Cetuximab, but the protocol that I used does not work. I would like to ask if someone else has one protocol, please send it to me.

04 May 2014 2,410 6 View

Colon cancer cells bearing KRAS and Chemotherapy Drug Effectivness

What we know: We know that ~35-45% of colorectal cancer cells bear the KRAS mutation. Prognostic significance of KRAS gene mutations in colorectal... We know that certain chemotherapy drugs are...

01 January 1970 7,000 1 View

Colon cancer cells bearing KRAS and Chemotherapy Drug Effectivness

What we know: We know that ~35-45% of colorectal cancer cells bear the KRAS mutation. Prognostic significance of KRAS gene mutations in colorectal... We know that certain chemotherapy drugs are...

01 January 1970 1,488 4 View