Hello,

I am a geologist whose mother-in-law's death has raised many doubts. During a TURB procedure for bladder cancer, a urinary fistula developed. Since the patient passed away six months later due to metastatic invasion, it is suspected that excessive ablation of the bladder wall during tumor removal caused a perforation, leading to urine leakage, as confirmed by a CT scan performed four days later. This urine, mixed with cancerous cells, may have spread into the peritoneum up to the liver. A total-body contrast-enhanced CT scan, conducted just hours before the patient’s death while she was in a coma, revealed liver lesions and metastases in the liver, lungs, and brain.

Is there any literature supporting the peritoneal dissemination of cancerous cells mixed with urine that could have led to widespread liver metastases and/or secondary tumors?

Thank you in advance.

Giacomo Malvasi