Can you suggest some software or web-services that perform restriction analysis for DNA sequence containing single nucleotide polymorphism (SNP)? Is there any software that provides comparative analysis i.e. can suggest allele-specific enzymes?
I am not a bioinformatician, but hope following information is helpful.
Maybe this is also interesting?! http://www.ncbi.nlm.nih.gov/pubmed/15774022
hello Karpov,
you can use the following sites to find you SNP of interest:
http://fastsnp.ibms.sinica.edu.tw/pages/input_CandidateGeneSearch.jsp
http://compbio.cs.queensu.ca/F-SNP/
http://snp.ims.u-tokyo.ac.jp/search.html
http://www.ncbi.nlm.nih.gov/projects/SNP/
in order to find a specific enzyme for you SNP you can use the following bioinformatic tools:
http://tools.neb.com/NEBcutter2/
http://tools.neb.com/REBsites/index.php
good work
Thank you very much! Great suggestions!
Try this one, may be easy to use. http://www.ebi.ac.uk/interpro/
I agree with Sergio. Usually I use http://tools.neb.com/NEBcutter2/ or http://www.fermentas.com/en/tools
I think DNA STAR
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