who can help me to find the solvent for acrylamide hydrogels? among these solvents which one is suitable for NMR analysis? Please also help me to find the purity and range of these materials.
1- CDCl3
2- D2O
3- Aseton-d
4- DMSO
5- Metanol-d
Regards
hydrogels are crosslinked 3D polymeric network and do not dissolve in solvents. they only swell in solvents.
Dear all,
to Dr. M. Yadollahi, not all gels have permanent (chemical bonds) crosslinks, the one you mentioned is only half of the whole familly of gels, since most of gels are physically (entanglements mainly) crosslinked.
So, it is for Dr. Farzaneh Sabbagh to specify which type of hydrogels she is dealing with. In all cases and since you are dealing with acrylamide, I think Deuteurated water D2O is the simplest and the cheapest. The important thing is that the signal of the solvant should be far away from those of the gel for better interpretation.
The second part of the question is a little bit unclear, which concerns ' the purity and range of these materials'. Please clarify more. Regards
For crosslinked gels, you can dry them then reswell in the NMR solvent (D2O typical for hydrogels). Just need the dimensions such that they can fit into the NMR tube (may be easier to resell the dry gel in D2O within the NMR tube itself).
Really Thank you for helping me to find out the correct solvent. Could you please also say me your idea about the range and purity of the D2O?
Regards
Dear all,
most solvents designed for NMR spectroscopy are of high purity. D2O of sigma aldrich is higher than 99.999%¨purty. The attached documents may bring additional information. Regards
Dear all,
additional documents that may help in answering this question. Regards