Can I inject Brefeldin A i.p.?

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Benjamin G Vincent

Hi Ela. Looks like this has been done at 250ug i.p. 6 hours prior to harvesting tissues for analysis: Sega et al (2014) PLoS One 9(1): e86551.

-Benjamin

Ela Elyada

Thanks!!

Huifang Tang

Yes, you can. Intraperitoneal (mouse) LD50: 200 mg/kg ( Material Safety Data Sheet. Brefeldin A (BFA) sc-200861" (PDF). Santa Cruz Biotechnology. 20 January 2009. ) , and : Intraperitoneal LD50 (mouse): 250 mg/kg; Oral LD50 (rat): 275 mg/kg; ( "SAFETY DATA SHEET Brefeldin A" (PDF). Cayman Chemical. 6 February 2015. )