How should I consider a negative value of the I squared during the heterogeneity assessment in meta-analyses?

I'm doing the heterogeneity calculations in a meta-analysis. The I squared values are sometimes negative. How should I consider such a negative values?

20 November 2017 1,576 5 View

Intrahepatic Cholestasis of Pregnancy

Following, a link for answering to some questions on Intraepathic Cholestasis of Pregnancy The survey is organized by th Clinical & Experimental Obstetrics and Gynecology Journal and results...

01 January 1970 8,590 6 View

Should the AUC in a concentration-time graph of a subcutaneous implant be roughly the same for poeple?

I have 2 concentration time curves of a subcut drug implant. the first group has a peak around the 50 day mark where as the second group does not. Both groups received the same implant by the same...

10 February 2021 2,305 3 View

Separated objects vs Non-Manifold Assembly?

I'm trying to do a simulation between the Maxilla and the Mandible I converted the Dicom file from the CT scan to a CAD module and module the articular discs via 3d software. I have two options...

08 February 2021 8,731 2 View

How to fix and protect blood clots for histology ?

Hi, I encounter some problems, I need to my research to fix and cryoprotec some blood clot for histology analyses. Mys current protocol is the following : 48h of para formaldehyde 4% and 7 days of...

07 February 2021 3,756 3 View

How do I keep my prefixed (PFA) frozen tissue sections from lifting off the slide?

I'm trying to stain mouse lung tissue IHC-IF I fix in 4% PFA overnight immediately upon harvesting tissues Then dehydrate/cryoprotect in sucrose gradients 15% to 30% Then freeze in OCT media...

06 February 2021 2,336 3 View

How to perform CV by using potentiostat?

I have deposited a metal oxide thin film of glass plate, A conductive thin film was also deposited on the glass substrate before the deposition of metal oxide film. How can I perform its CV from a...

01 February 2021 7,710 3 View

Antibody dilution for IHQ in OCT frozen tissue is more similar to IHC in Paraffin-embedded samples or to Immunocytochemistry?

31 January 2021 8,678 3 View

STS Score - Excel sheet calculator?

I'm looking for an excel sheet to calculate the STS Score. From the website http://riskcalc.sts.org/stswebriskcalc/calculate. Does anyone have a worksheet to calculate the STS Score?

25 January 2021 958 4 View

I have tissue sections on Superfrost Slides (NOT Plus) and they fall off during IF. Any suggestion?

Hi, I have OCT embedded tissue cut on Superfrost slides. However these slides are not Superfrost Plus, so apparently they are not coated. During IF all my sections are lost. How can I save them?...

18 January 2021 5,256 2 View

Does early COVID 19 treatment matter ?

The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness, hospitalizations, and death. The complex and multifaceted pathophysiology of life-threatening COVID-19...

29 December 2020 7,446 4 View

What cryostat temperature is optimal to collect frozen 14 micron thick vagus nerve sections?

Hi, I'm going to section vagus nerve tissue embedded in OCT, collecting 14 micron thick sections. What cryostat temperature is optimal for colleting these sections?

01 December 2020 4,400 2 View