Following, a link for answering to some questions on Intraepathic Cholestasis of Pregnancy
The survey is organized by th Clinical & Experimental Obstetrics and Gynecology Journal and results will be published on that journal (open).
I thank in advace people who will answer
Dr Ugo Indraccolo, M.D., Ph.D.
https://zh.surveymonkey.com/r/VPXL6MH
1. IHCP is noticed as early as 26 weeks.
2. By 32 weeks damage is done .
3.Most become asymptomatic at 37 weeks.
4 . Predictor for adverse fetal outcome cannot be pinpointed .
5. By this logic all should receive steroid and deliver by 32 weeks.
6. I have seen case postpartum unexplained IUD with no risk factors in mother other than IUD.
Point no 6 ...read postpartum fetal demise with no other risk factors other than IHCP.
Thank you for your kindly precisations. I will consider your points when I will comment results of the survey.
Your,
Ugo
1. As per available literature neurological and cardiac damage is done by 28 - 32 weeks inspite of UDCA.
2. It has been noticed that levels of enzymes including LDH have no correlation with neonatal outcome.
3. We give UDCA, Periactin , Inj Vit K ( 3 doses) , Dexamethasone and inspite of that observe IUD, Early neonatal death, Pulmonary haemorrhage, and all are unpredictable inspite of delivery at 37 weeks.
4. Tried to submit the form it ends in Mandarin.
The Chinese text at the end does not relate with the survey. Don't worry. Again, I thank you.
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