I am currently working with TNBS model of ulcerative colitis in rats to evaluate the effect of an Ayurvedic drug which is used in grahini roga. It will be very helpful if anyone will help me by discussing the pathogenesis of grahini roga.
If anyone who have Atisar (diarrhea) and get well after treatment, but due to poor food habit, for example eating food before feeling hungry, may cause disturbance in enzymatic action (Agnimandya and Ajirna) which may lead to Grahani
Hello Yadu Nandan Dey , I am sharing my view as below:
I considered it as Grahani Dosha and not as a Grahani Roga. Every human individual is different from each other based on his Prakriti (Body Constitution). Symptoms present in the patients are may or may not be similar, but the treatment approach is based on Hetu (Causative factors) responsible for imbalance of Agni (Digestive Fire) and disturbed equilibrium of Tridosha which ultimately responsible for the Grahani Dosha. The major causative factors responsible for the Grahani Dosha are Improper food Habits, Stress, Lack of sleep and faulty treatment of recurrent episodes of Atisara (Diarrhea). The treatment approach is also depend on state of disease and patients body constitution, Digestive fire, Food habitat etc. It is not a right approach to use a single medicine in all the patients and customized treatment approach for each patient is more beneficial.