Are there good, affordable, sources of aggregation-prone Tau expressing cell lines?

02 February 2020 1 8K Report

Does anyone know of a good, commercial source for a cell line that expresses an aggregation prone Tau protein (e.g. P301L Tau), preferably in a well-characterized background (e.g. SY5Y).

I don't see useful lines on ATCC and the quote I got from Innoprot weren't affordable (several $K a piece - https://innoprot.com/product/green-fluorescent-tau-sh-sy5y-cell-line/).

At that price I'm considering transfecting an AddGene vector in HEK293T, but I'd prefer to avoid the hassle as long as it won't cost me a fortune.

Yuan Yu

Hi Brian, I recommend Creative Biogene. They have successfully generated hundreds of stable cell lines and they can also offer related vector products. Maybe they can help you. Good luck!

https://www.creative-biogene.com/products/transfected-stable-cell-lines.html

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