Hello all, anyone who can advice me on how to get efficient transduction of AAV9-virus in skeletal muscle of adult mice? I saw paper talking about tail-vein injection but in my hands it did not work at all .. Any suggestions?
Hi Valentina, in situ injection of AAV to infect skeletal muscle is a best way, we always got a good infection.
You could find more information on this website:
www.genemedi.net/i/aav-packaging
Hi Valentina
Intravitreal injection is the best for systemic expression. For local (muscle) expression intramuscular is very efficient.
Best
Karim
Hi Valentina, in situ injection of AAV to infect skeletal muscle is a best way, we always got a good infection.
You could find more information on this website:
www.genemedi.net/i/aav-packaging
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