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Questions related from Paulo Magno Martins Dourado
I will start an experimental study in infarcted rats to evaluate the additional role of statins in myocardial protection. I think of studying two drugs: pitavastatin and rosuvastatin in various...
23 May 2016 129 5 View
Following ST Elevation Myocardial Infarction (STEMI) the myocardial ischemia causes an inflammatory response, which is a predictor of mortality and myocardial remodeling. Treatment with statins...
03 September 2015 1,181 9 View
The high cost of diagnostic methods, even of biochemical markers, limit many of the tools necessary for the diagnosis of CAD, especially if we consider the group of low-risk patients. Can CRP be a...
01 September 2015 3,478 9 View
Some studies showed that eNOS-derived reactive oxygen species play an important role in atherosclerosis progression and restoration of eNOS functionality by upregulation of GCH1 is a rational...
19 April 2015 9,071 4 View
LDL cholesterol remains the proven target. Many alternatives have been presented. The possibilities debated involved cholesteryl ester transfer (CETP) protein inhibitors, apolipoprotein B (apoB)...
08 April 2015 6,510 11 View
Dyslipidemia is related to the progression of atherosclerosis. Although treatment of dyslipidemia is beneficial in decreasing the number of coronary events its effect on infarct size and...
08 April 2015 1,383 15 View
The essential logic is to decrease the time of exposure to cardiovascular risk factors with genetic insights providing strong justification for this approach. Lifetime exposure to lower...
28 March 2015 8,647 26 View
A new class of cholesterol drugs - the PCSK9 inhibitors - might reduce the risk of heart attacks and strokes, and some trials were recently presented demonstrating these evidences, but we do not...
17 March 2015 3,394 5 View
With the increasing use of echocardiographic contrast for both endocardial border delineation , and in the evaluation of myocardial perfusion , we are faced with the indication for the procedure...
14 March 2015 9,063 5 View
Statins are the main weapon in the fight against cholesterol, which enabled reduction of morbidity and mortality, however many patients do not tolerate it and others do not reach the recommended...
08 October 2014 7,130 11 View
Recent studies have shown to be feasible the use of thrombolysis by ultrasound. This is really a new therapeutic window? What we need to move forward to achieve this purpose?
14 September 2014 6,192 3 View
Recent studies have reported an increased use of 3D stress echo in the diagnosis of coronary artery disease. This method really is ready for use in clinical practice?
01 September 2014 320 4 View
I'm developing an experimental study in mice in which need to determine the presence of peripheral arterial disease and I would like to establish the best strategy to define this clinical situation.
29 August 2014 2,108 5 View
The indication for echocardiography to evaluate systolic function of the left ventricle represents a major clinical applications of this method and new diagnostic techniques have been proposed....
19 August 2014 7,171 9 View
I'm developing a new survey that measured blood flow by Doppler echocardiography in mice will be necessary to determine the degree of residual flow after femoral artery stenosis and I would like...
18 August 2014 2,823 4 View
In the setting of acute myocardial infarction (AMI) reduced LV ejection fraction adversely influence evolutive prognosis and some parameters have been used to evaluate prognosis as degree of...
09 June 2014 6,255 3 View
NADPH oxidase hyperactivation is an important source of ROS production and consequently leads to myocardial infarction induced atrophy and some studies have shown that cardiac dysfunction after MI...
24 May 2014 445 0 View
I wonder how much stress echo is appropriate in managing patients with CAD.
01 May 2014 9,470 5 View
I wonder what would be best way to evaluate the role of inflammatory cytokines in outpatient clinical trials in acute myocardial infraction?
27 April 2014 2,026 10 View
I wonder what kind of echo stress contributes most to the diagnosis of myocardial viability, and if the addition of the strain can add value to the method.
20 April 2014 1,409 3 View
I'm interested to know if you can add strain to stress echocardiography to improve the accuracy of the method for the diagnosis of coronary artery disease and the best strategy (longitudinal...
14 April 2014 732 4 View
I would like to know if the area with a perfusional defect on a contrast echocardiography corresponds to the site of future myocardial infarction.
05 April 2014 2,858 4 View
I am interested in knowing the ways of high levels of dysfunctional HDL in the acute phase of myocardial infarction induce minor flow-mediated dilation and nitric oxide production and the...
29 March 2014 5,037 1 View
I would like to know about the strategies that are being developed to evaluate the role of peri-coronary fat in the development of coronary artery disease, mainly on the use of cardiac imaging and...
05 March 2014 8,353 3 View
What intensity of ultrasound energy is used to dissolve thrombi and is there a standard protocol available?
26 February 2014 2,002 8 View
What is the best strategy - tredamill stress test or chemical stress with dipyridamole or dobutamine?
24 February 2014 2,019 7 View
I would like what is the methods you are using to evaluate paradoxical low flow low gradient aortic stenosis
17 February 2014 2,177 18 View
