Anyone has any experience with YB2 cells ? Compared batch and fed-batch cultures (induplicate) and 2 different time. Batch mode lasted 7 days, peak VCD 8 -10E6 cells/mL, titer 200ug/mL. Fed-batch mode (glucose was added whenever below 2g/L), lasted 10-11 days, peak VCD 12 - 14E6 cells/mL, titer 180 ug/mL. I tried to explain the difference because in batch mode, the cells were pressured to secrete more Ab (?) Fed-batch just had the cells grow more. Is that right ? It's very different with the other cell lines. Fed-batch always had a better titer than the batch culture ! Could you kindly give me more input about YB2 cells. Thank you so much in advance ...