Why Tau 46 is considered as a biomarker for taupathies?

12 December 2018 0 5K Report

Hi,

Tau 46 antibody is used to tag total tau. What does total tau mean? Tau isoforms + phosphorylated tau? In IHC, I observe positive staining in transgenic mice (Tg4510) hippocampus, and in wildtype no staining at all.

Thanks in advance!

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