Why some people favor sleeping beauty more than cre-lox system for lineage tracing, vice versa?

21 June 2022 0 8K Report

Lineage tracing can be done by activating reporter gene which is positioned next to stop codon. Some people use cre-lox system as the reporter transcription controller, the others favor HSB-transposase. Is there any reasons behind this (maybe cell-dependent, etc.)?

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