You can take a look at Wobble base pair

A wobble base pair is a pairing between two nucleotides in RNA molecules that does not follow Watson-Crick base pair rules.

The wobble position of a codon refers to the 3rd nucleotide in a codon. This nucleotide has two major characteristics:

For further reading: https://en.wikipedia.org/wiki/Wobble_base_pair

Are you referring to "codon bias" where there are differences in the frequencies of synonymous codons?

Here's a very nice publication that addresses that codon bias and how that affects protein expression:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794256/

Thanks for reply

if silence mutation occured but both( before and after mutation) the codon gives the same protein but this protein has different activity 🤔