There are many factors that determine the toxicity of nanoparticles, so that each nanoparticle is to be considered separately for its toxicity, that is for its undesired effects on the cell activity. In the case of CuO and ZnO, both are cited [1] as causing damage to the cell membrane. ZnO is cited [1] as affecting cell morphology, causing DNA damage, etc.
[1] H Bahadar et al., Toxicity of Nanoparticles and an Overview of Current
Experimental Models: Article Toxicity of Nanoparticles and an Overview of Current Experim...
You can go through these article -
1. Article The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles
2.Article Investigating the Toxicity of Cu, CuO and ZnO Nanoparticles ...
3. Article Accumulation and Toxicity of CuO and ZnO Nanoparticles Throu...
Elements or ions of copper and zinc are part of the enzymes in our body. Therefore, their increase or deletion affects their work. Blocking the work of dehydrogenases by closing the "pocket" with zinc at its bottom leads to the death of E. coli.
Article Mirgorod Yu.A., Mikhno I.L .Taran V.V. The mechanism of acti...
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