I would like to know the wild type and mutant type allele of rs1344706 but some time I find it A/C and some times I find it G/T.
Is this has anything to do with NCBI assay ID?
Will a SNP has the same (ss) ID or will it change?
Paste the sequence of the SNP into this box, press "Reverse Complement" and your question will be answered:
http://reverse-complement.com/
I believe you are just finding the same SNP sequence from both forward and reverse strand.
Dear Mona,
I would advise you to use Ensembl nomenclature (https://www.ensembl.org).
Such situations happen as historically scientists reported the results from different DNA chains, complementary sequences etc.
My recommendation is to use RS ids of the SNPs, as all records in the database are merging in the end under RS code.
Good luck!
Please check
1. Gorlov IP, Gorlova OY, Amos CI (2015) Allelic Spectra of Risk SNPs Are Different for Environment/Lifestyle Dependent versus Independent Diseases. PLoS Genet 11(7): e1005371. https://doi.org/10.1371/journal.pgen.1005371
2. Pinglang Wang , Manhong Dai , Weijian Xuan , Richard C. McEachin , Anne U. Jackson , Laura J. Scott , Brian Athey , Stanley J. Watson and Fan Meng .SNP Function Portal: a web database for exploring the function implication of SNP alleles . BIOINFORMATICS; Vol. 22 no. 14 2006, pages e523–e529
3. Tom W. J. Huizinga, David S. Pisetsky, and Robert P. Kimberly .Associations, Populations, and the Truth Recommendations for Genetic Association Studies in Arthritis & Rheumatism . ARTHRITIS & RHEUMATISM Vol. 50, No. 7, July 2004, pp 2066–2071
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