Which type of sample (Blood or Tissue) is better to understand biomarkers or key signatures involved for a particular disease?

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Nurul Ridzuan

Basically it depends on the mechanism of that particular disease and also the nature of specific biomarkers that you will be looking at. Some markers are high expressed in the blood circulation and some are actively produced/working in the tissue itself. Before you proceed, you may check the mechanism/pathology of that particular disease you are working on.

Ananda Chandrasekara

I hope this articles will help you to identify suitable biomarker.

Detection of human breast cancer cells using a 2-deoxy-D-glucose-functionalized superparamagnetic iron oxide nanoparticles (Cancer Biomarkers, vol. Preprint, no. Preprint, pp. 1-8, 2017)

Cell membrane and intracellular expression of toll-like receptor 9 (TLR9) in colorectal cancer and breast cancer cell-lines(Cancer Biomarkers, vol. Preprint, no. Preprint, pp. 1-6, 2017)

Kamel Charradi

I am agree with the answer of Nurul Ridzuan