Which statistical test is optimal for assessing drug synergy?

08 August 2016 1 2K Report

I came across several statistical tests to assess synergy between 2 drugs, among which are the Chou Talalay method and Bliss Independence model. Which one is optimal?

And can the Chou Talalay method be calculated manually without the use of Compusyn software?

Thanks.

Patrick

Ronán Michael Conroy

You could use R to do the Chou Talalay calculation. See Journal of Statistical Software, here: https://www.jstatsoft.org/article/view/v034i06

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