Which kind of drug therapy or molecule class can be prescribed to the renal impaired diabetic patient?
I'm not a specialist in the field of this question but think that the paper linked below might be a good reference for you.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956196/
Dear Sir
GLP1 mimetic drugs like Albiglutide, and the DPP4 inhibitor linagliptin. Recently there is talks about the safety of metformin in mild renal impairment. As all of us know metformin is currently contraindicated if the serum creatinine is above 1.4mg in men and even lower in women.
The attached PPT summarized antidiabetic Therapy in Patients with Chronic Kidney Diseas
In these days we are treating a woman with a lactic acidosis induced by metformin in a pt with pulmonary acute infection , vomiting and diarrhea . General practitioners must be allerted about the risks linked to the use of metformin in pt with kidney failure even if the common idea is that metformin is not dangerous with a kidney function of 60 ml/min . But when a pt is affected by a pulmonay infection or by vomiting ? So we prefer Repaglinide that is excreted completely through bile .
The most safe anti diabetic class in these patients ( after insulin) is thiazolidindions , like Pioglithasone (Pitoz or Glutasone) ..
- Badges
- Science topic
- Similar topics
- Biological Science
- Molecular Cell Biology
- Culture Cells
- Cell Line