Many research demonstrate alcohol inhibits inhibitory GABA neuron in VTA and increases dopamine in NAc.
But is there no dopamine increase in VTA?
VTA is the region responsible for rewarding, reinforcing and motivational beahviour. ethanol directly effect that area and induce relaease of DA. hope following articles would help you.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2544469/
https://www.ncbi.nlm.nih.gov/pubmed/10591603
What concentration of ethanol are you using and how are you administering it (e.g. iv or ip?)?
And how are you measuring dopamine? Are you using microdialysis or voltammetry? Are your probes definitely sampling from the VTA?
I inject 20% ethanol i.p and use microdialysis.
I check many time probe's position.
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