If we use an oil-immersion objective in dry conditions (air), will the maximum collection angle of the objective change?

What if we use an immersion oil objective in the air (medium between the objective and the sample)? Will the effective NA change? What about the maximum collection angle?

22 January 2020 7,842 1 View

Is 6-311G APFD-DFT++ a right choice for carrying out an opt+freq calculation of cyclopentyl methyl ether and cyclopentanol?

I want to optimize Cyclopentanol and cyclopentylmethyl ether using Gaussian.

12 January 2019 8,515 4 View

How to find structurally similar protein?

I have a protein obtained through ab initio modeling. I would like to know whether this protein is exhibiting any kind of structural similarities with other proteins available in the PDB. How I...

01 October 2017 7,058 4 View

Can any one suggest me how to compare the active sites of two different proteins?

I am trying to design multi-target directed ligands. I have found some similar common ligands for both proteins. When I docked these ligands I have seen the score is almost similar. But these...

08 March 2017 1,898 2 View

B factor comparison?

18 December 2016 3,013 3 View

Does anyone know how to train a matlab custom neural network in reinforced manner(Only using "adapt" function)?

09 September 2016 1,668 3 View

I have loaded dna in 0.8%gel at 85 v i saw the band after 45 min the band gone ..do dna run fast on 0.8% gell

crude dna size will be large know then how could it ran fast on 0.8%gel KIDNEY TISSUE DNA I have isolated and loaded to the well

26 April 2016 9,823 19 View

How to synthesize 4-sulfopthalic acid from phthalic acid at lab scale

Dear all, I want to synthesize sulfophthalic acid from Phthalic acid so i need a scheme of reaction to carryout this synthesis

16 February 2016 5,586 1 View

How can I do element birth and death for line elements in ABAQUS?

I modeled a steel lattice tower in abaqus using line element. i am applying seismic loads and want to delete the elements crossing the yield stress. i tried the same in visualization module -->...

17 March 2015 869 3 View

Can anyone help me analyze results from HIF1 western blots?

I am doing HIF1 westerns in southwestern HIF overexpressing mice liver and adipose tissue. I'm using novus antirabbit HIF1a antibody 1:1000 concentration overnight incubation and getting strong...

05 September 2014 9,823 7 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

What kind of fluid could I use for a pitfall trap that also does not invalidate molecular testing?

Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...

03 March 2021 5,978 5 View

Can linear DNA be used as template for site-directed mutagenesis?

Is it possible to induce site-directed substitution mutation by quick-change method on linear dsDNA? or it has to be cloned in some vector? If yes, should it be treated with the Dpn1 enzyme...

03 March 2021 401 4 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View