What is your experience in treatment of systemic symptomatic juvenile xanthogranuloma?

28 January 2015 0 9K Report

A 15 year old girl with Juvenile xanthogranuloma diagnosed by tissue biopsy and immunohistochemistry and presented with hand arthritis which was treated with prednisolon 20mg/d, Meloxicam, and Hydroxychloroquin 400m/d. It has good response, but when tapering steroid below 20mg , the symptoms recur again. What is your experience regarding other immunosuppressive drugs Like Methotrexate, Azathioprin,

Badges
Science topic

More Faiq Isho Gorial's questions See All

Are you a specialist in the field of artificial neural networks?

Dear Sir I welcome all researchers specialized in the field of artificial neural networks to conduct joint research in this specialty and its applications in engineering and science. If you would...

24 June 2023 8,262 0 View

What is the difference between a covariate and a confounder?

what is the difference between a covariate and a confounder?

15 June 2023 6,970 3 View

JCR list of 2023?

Distinguished researchers and scientists, I hope you all are doing well. In which month of 2023 will the JCR impact factor and quartile ranking of journals be released? thanks

07 June 2023 4,117 2 View

How endonuklease restriction enzyme indentify mutation in gene?

about mutation

20 May 2023 3,238 2 View

Controls for ChIP-qPCR?

Hi everyone, I am in search for positive and negative controls for some of Histone marks for ChIP-qPCR in HUDEP cells. Can anybody help in this matter? Marks are: H3K27ac H3K27me3 H3K4me3...

12 March 2023 5,833 2 View

If a protein has low intracellular expression levels, it is likely that the amount of protein secreted into the extracellular space will also be low?

if a protein has low intracellular expression levels, it is likely that the amount of protein secreted into the extracellular space will also be low?

06 March 2023 6,731 6 View

If protein expression in blood was low (detected by western blot) and protein level in serum (detected by ELISA) was high? what dose it mean?

Good day, If protein expression in blood monocytes was low (detected by western blot) and protein level in serum (detected by ELISA) was high? what dose it mean? Note: the protein should not...

22 February 2023 8,504 6 View

If gene expression is low for specific gene, does this mean when I measure the serum level by ELISA of protein expressed by this gene it will be low?

if gene expression is low in specific diseases based on previous research, But when I measured the protein expressed by the same gene in blood of same disease by ELISA I found high serum level?...

21 February 2023 320 4 View

How to implemented COSMO solvation moddel in ORCA by manually?

so how to prepare input file in ORCA manually,but ORCA does not have the COSMO solvation Moddel.please help me

03 February 2023 6,198 1 View

Hello, dear scientists and researchers! What is the most effective method for obtaining the colony after bacterial transformation?

Is there any specific reason that we cannot get the transferred colonies? According to our methods and protocols, we have done all the procedures of bacterial transformation and used plasmid pUC19...

11 November 2022 6,102 1 View

How to draw the five chelate rings of [Co(EDTA)]- on this picture?

Is this circle one of the rings?

03 August 2024 5,988 0 View

What is homomenthyl cinnamate?

the molecule name is citated in old literature about organic sunscreen molecules

10 July 2024 5,576 2 View

What causes unexplained rash on the whole body after consuming Stillnox and Serdep in patients on Jalramet, Reaptan, Aspavor, Chela-fer and Myoprin?

I want to understand what are the contraindications and side effects caused in diabetic patients who are on chronic medication (Stillnox and Serdep in patients on Jalramet, Reaptan, Aspavor,...

25 June 2024 984 0 View

Hello, currently I am working to develop biopesticide product use Metarhizium. I would like to know how to formulate it so it can be effective?

Currently, I am working in oil palm plantation industry. This Metarhizium will be used to control the population of pest Oryctes rhinoceros. I need clue to formulate Metarhizium so it can be...

24 June 2024 9,926 3 View

I need to buy reducing agent Bruggolite FF6 M, how can I buy?

I have searched for CAS no. but cannot find.

24 June 2024 2,737 2 View

What is the potential role of phytochemicals in the prevention and management of asthma symptoms?

Asthma is a chronic respiratory condition marked by inflammation and narrowing of the airways. While traditional treatments involve medications like corticosteroids and bronchodilators, there's...

14 June 2024 8,063 2 View

For nuclei extraction from human cells, can I replace EGTA with EDTA in lysis buffer?

I understand that there are differences in ion preference as far as chelation is concerned when comparing EGTA vs EDTA. But is it ok to replace EGTA in my lysis buffer with EDTA since EDTA...

10 June 2024 1,188 1 View

How can I avoid interaction of plant based reducing agents to final nanocomposite for in situ preparation og Ag doped GO-Fe3O4 nanocomposite?

Can anyone comment on the following concerns I want to synthesize Ag doped GO-Fe3O4 nanocomposite in situ using plant extract as green method for Ag+ reduction. What will be the effect of plant...

23 May 2024 5,244 2 View

What concentrations should be selected for hemolytic assay for antimicrobials?

I am performing hemolysis assay for antimicrobials but there's difficulty in selecting the concentrations of the antimicrobials. I have read the papers and MHC 90 was determined. Should I consider...

21 May 2024 8,912 3 View

How to know if complexed Mn(II) has been (air-)oxidized to Mn(III)?

We have synthesized a polymer that attains a fairly good removal of manganese ions from synthetic waters contaminated with MnCl2. After many tests, we have deemed it a decent adsorbent. All in...

14 May 2024 1,811 2 View