Dear Roberta,

Homomenthylcinnamate is the ester made from trimethyl-3,3,5 cyclohexanol (also known as homomenthol with CAS RN 116-02-9) and cinnamic acid.

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Homomenthyl cinnamate, commonly referred to as homosalate, is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol. It is widely utilized in dermatological formulations, particularly sunscreens, due to its ability to absorb ultraviolet B (UVB) radiation in the 280–320 nm range. This compound plays a crucial role in photoprotection, preventing erythema and potential DNA damage induced by UV exposure. Its chemical properties, including moderate lipophilicity, enhance its skin penetration and compatibility with other organic UV filters, thereby contributing to the formulation of broad-spectrum sun protection products. Homosalate's stability, photostability, and safety profile are subjects of ongoing research, especially in the context of its potential endocrine-disrupting effects and environmental impact.