drug and beta cyclodextrin form a inclusion complex, how the drug is released
I'm new to primary human fibroblast culture and I'm studying aging using cells from old and young donors. Some research groups have used media supplemented with FGF2, so I cultured cells in the...
29 July 2024 3,030 2 View
The question seeks to identify whether the concept of diplomacy works as a mechanism that can remedy the current problem involve the invasion of a sovereign state like in the case of Russia...
14 May 2024 2,034 5 View
The question aims to explain the basic interconnection of international security in relation to the concept of balance of power
06 May 2024 861 7 View
I recently did some calcination (500C) on a hydrated powder material in three sets of experiments. The experiments only differ in the moisture content of the calciner i.e. 0, 40 and 80%. Then I...
24 January 2024 7,291 0 View
I extracted feces and plasma by the method below. 1. Feces 50 mg + water 1 mL 2. Plasma 100 µL + methanol 400 µL And 1 uL was injected into HPLC for thiamine analysis. When 1.1117 µM of glutmic...
13 May 2023 4,294 0 View
Regarding the clay minerals, what is the phase of alumina? delta, gamma, theta or alpha? In a separate question, what occurs to this phase after calcination at around 800 C?
16 October 2022 5,560 7 View
Subject: Monitoring crack propagation in compression Hi everyone, I am simulating the behaviour of some components that are under compression in ABAQUS, including fracture and element deletion....
25 February 2021 9,890 0 View
mixed graphite with silver chloride solution and got a film like substance. Can anyone explain what it maybe?.Actually i processes it for making reference electrodes
09 November 2020 7,523 1 View
I am running the tensile experiment (polymer material) in Abaqus explicit with the Ramberg model. But the solution exists with an error. It's showing "The keyword is not existed in explicit". Then...
13 July 2020 5,730 1 View
This is a DSC plot of a two minutes acid-etched copper plate.
17 February 2020 2,499 2 View
I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...
07 August 2024 2,283 2 View
I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...
03 August 2024 4,725 2 View
Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...
03 August 2024 2,730 1 View
Hi guys If anyone is currently working on aging cells, you guys would like to give me some advice. I'm testing against biomarker (SA-beta-Gal), I encountered a false positive in the control group...
02 August 2024 6,735 1 View
I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...
24 July 2024 8,696 0 View
Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...
19 July 2024 2,155 0 View
How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...
15 July 2024 4,192 1 View
Hi, In the 6 well plate, when I am seeding the cells. Do I add 1ml of complete media to one of the wells for the control at this stage or do I wait unit I am treating the plates to do that? Also...
13 July 2024 9,783 1 View
In my country, there is a lot of public outcry in relation to the presence of drug injection and related behaviors in public. Hence at least the bigger cities would probably benefit from the...
08 July 2024 8,903 1 View
Hello everyone reading this topic! It is well known that microcrystalline cellulose 102 is recommended for use in direct compression technology, however, like other grades, it has poor flowability...
08 July 2024 2,807 0 View