What is the stiffness of Geltrex gels?

10 June 2021 1 5K Report

Is there any published literature available on the stiffness of 100% Geltrex gels (reconstituted basement membrane matrix from EHS tumor, Thermo)? This is not a parameter that is mentioned by the vendor and I'm trying to compare it with the known stiffness of ColTgel (transglutaminase crosslinked gelatin gel). Any leads would be appreciated, thanks!

Elodie Vandenhaute

This is quite late but it might help someone else. Since Geltrex hydrogels are similar to Matrigel ones, I would say the maximum stiffness is around 300 Pa (see Corning website: https://www.corning.com/catalog/cls/documents/application-notes/CLS-AC-AN-449.pdf).

This is quite low compared to any decellularized tissue, so to in vivo situation.

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