Hi everyone,
I am currently working with UNC569 (HY-117596) but I am unsure about its solubility. Could you please advise which solvent works best for dissolving it?
Also, if you have any recommendations on the ideal dissolution concentration and method, I would greatly appreciate it.
Thank you for your help!
Hi Janice, we’ve tested several approaches for dissolving UNC569 (HY-117596) and found the following options work well:
If the compound takes time to dissolve, you can use a 20–30 kHz ultrasonic bath (not a probe sonicator), or alternate between 37°C heating and vortex mixing to help the process along. Hope this answer helps to solve your issue.
The answer to this question comes from MCE Technical Support.
Lucian Miles
UNC569 (HY-117596) Solubility & Dissolution (Short Guide):
- Best solvent: DMSO
- Solubility: ≥10 mM in DMSO
- Poorly soluble: in water, PBS, ethanol
Dissolution method:
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