Shreya Sinha It depends on how complete your question is. Synthesis of colloidal gold particles does not need a nitrogen atmosphere. Also see:

https://www.researchgate.net/post/Why_some_mixtures_containing_nanoparticles_should_be_agitated_under_a_nitrogen_atmosphere

Other alternatives such as Ar or He may be inconvenient or expensive.

Shreya Sinha, in most of the synthesis process you don't want oxidation by products in your nanoparticles, Nitrogen provides you inert environment that helps to reduce the oxidation and any contamination during synthesis.

Nanoparticle synthesis is a fine skill. Depending on the size and morphology control a lot of conditions can be present. I am assuming the nanoparticles you’re synthesizing are not supported nanoparticles. In that case possibly you’d use a capping agent which might protect the Nps from becoming unstable.

But as pointed out by others the reoxidation of Nps might be an issue. Hence, I’d suggest read at least 3 more papers before diving into the synthesis. May be your system doesn’t need inert atmosphere as you’re thinking. But do not do any step without at least 3-4 literature support (ideally published within last 5 years). Often there is a synthetic development and a better (less labor intensive) method is developed.

Thank you Puranjan Chatterjee for your response. I will surely look further in literature before employing it.

Alan F Rawle

Thank you for sharing it sir. It is very helpful

Rahul Singh

Sir, Is there any other alternative ?

The role of using a nitrogen atmosphere during the synthesis of nanoparticles is primarily to prevent the oxidation of nanoparticles and to create a controlled, inert environment. This is especially important when dealing with metals or other substances that readily react with oxygen.

Nitrogen, being an inert gas, doesn't react with the nanoparticles or interfere with the reactions involved in nanoparticle synthesis. It essentially "protects" the nanoparticles from unwanted reactions with oxygen, moisture, or other substances in the air that could affect the nanoparticle's properties or morphology.

For example, in synthesising metal nanoparticles, exposure to oxygen can result in forming an oxide layer on the nanoparticle surface, altering the nanoparticle's physical and chemical properties. Using a nitrogen atmosphere can prevent this and help maintain the purity of the nanoparticles.

As for alternatives, other inert gases like argon or helium can also be used, depending on the specific requirements of the nanoparticle synthesis process. Argon, like nitrogen, is commonly used because it's relatively inexpensive and readily available. Helium might be used in specific situations where its unique properties are beneficial, but it's generally more expensive.

Remember that the choice of the atmosphere (nitrogen, argon, helium, or even vacuum) will depend on the type of nanoparticles you're synthesizing and the specific reactions involved in their formation. Always refer to the relevant scientific literature or consult with an expert when planning your nanoparticle synthesis protocol.

Joshua Depiver Thank you so much for your response sir. Its really helpful.