What is the role of interferon gamma in the growth of mycobacterium?

07 October 2013 1 4K Report

Does it promote or inhibit its growth?

IFN-Gamma in fact secrets by APCs and Th1cells and activate the MQ cells which engulf and inhibit the mycobacterium growth. But mycobacterium has ability to grow even in MQs. Finally the challenge between MQ and mycobacterium results in tubercle lesion that is a limited region for mycobacterium.

Badges
Science method

More Mohammad Aqdas's questions See All

Binder for ZnO nanoparticles in graphite paste electrode?

I have been using paraffin, but the deposited ZnO still detach from electrode. What is the best binder to modify graphite paste electrode with ZnO nanoparticles?

03 August 2024 4,624 3 View

If the emission of all greenhouse gases is stopped now, will the temperature of the earth continue to rise?

Here's a serious question: If we were to stop emitting all greenhouse gases right now, would the Earth's temperature start to cool down, or would the existing greenhouse gases continue to warm the...

30 July 2024 5,123 4 View

Wrong out put for gmx x2top?

Dear users, I would like to simulate a zeolite structure in gromacs. I got the .cif file from IZA expanded in one direction in Materials Studio and exported a .pdb file. However, when I want to...

24 July 2024 367 4 View

Is there a good macro photography kit for on-site metallurgical investigation?

I am looking to purchase a photography kit for onsite metallurgical investigations, such as capturing photos of worn areas, hot tears, cold tears etc. Could anyone suggest me a good...

22 July 2024 3,490 2 View

The measurement of cellular uptake of nanoparticles?

What protocol can be used to measure the cellular uptake of a nanoparticle? Is there a way to get more of a non-targeted nanoparticle into the cell? Why a fluorescent nanoparticle does not enter...

18 July 2024 7,153 2 View

How to define a zeolite structure with rigid framwork?

Dear Gromacs users, I would like to simulate a zeolite-water system. In different literature, it is suggested to consider a rigid framework of zeolite to decrease the computational cost. I would...

15 July 2024 4,590 1 View

How to classify 3D Bioprinting as a part of Additive Manufacturing?

Hello, I have a problem in classification of "Additive Manufacturing" techniques. There are several classification for Additive Manufacturing e.g. Powder, Extrusion, Resin etc. Actually, I am OK...

15 July 2024 139 3 View

Is there a difference between the curriculum and the style of the study?

A question about scientific methodology

13 July 2024 2,160 8 View

How to calculate Cohen's d from CI 95 and t value from a paired sample t test?

We have conducted a systematic review to investigate the effectiveness of a treatment for a psychological disorder. We aim to report effect sizes and p values of the reviewed studies but one study...

10 July 2024 7,186 4 View

Authorship for data analysis?

I participated in 2 research projects in which I was responsible for part of data analysis and figures production. Also, I spent hours trying a new statistical approach -for me- to implement in...

10 July 2024 1,226 5 View

Can we use technical replicates for statistical analysis of multiplex cytokine data?

I have done an experiment using luminex technique, measuring 46 analytes. but my sample size is less (N=6, for case and control each). However, i have put up the experimental set in duplicates....

31 July 2024 3,665 3 View

Ideal tissue thickness for multiple immunolabelling and confocal microscopy?

Hi there! I'm hoping to to look at co-localisation of cytokines and markers of different brain cell types (e.g., neurons, astrocytes, microglia) in juvenile rat brains (postnatal day 28) that have...

23 July 2024 2,844 1 View

Does HEK293T cell express RIG1?

Is there any benefit in knocking out the interferon receptor in 293T cells? In the context of creating RNA viruses 📷

13 July 2024 3,382 0 View

Motivational systems bind perception and behavior?

It was gestalt psychologists that took issue with elementalism (Kohler 1929), that all perception/consciousness can be broken down into component parts. The expression ‘the whole is greater than...

16 June 2024 9,199 0 View

?How can we study proton radius with a 600keV high luminosity gamma ray ?? mark: gamma ray; proton; ?

Our gg collider will make a high luminosity gamma ray beam: 600keV, 10^9photon/pulse, 50Hz, small emittance angle:2.5mrad. We want to know how can use this gamma beam to study the characteristics...

03 June 2024 6,849 0 View

Does RAW 264.7 cells express MI like marker CD86?

I have come across literature that RAW 264.7 are M1 biased, do they express CD86 without LPS/ IFN stimulation?

27 May 2024 6,359 1 View

Mouse MSCs not expressing TSG-6 on cytokine stimulation?

I am using mouse bone marrow derived MSCs (passgae 3-6) for my in vitro cytokine priming experiment. My basal media is 2% FBS-DMEM. I am using 10 ng/ml TNF-a, or IFN-g or both for 24 hours. I see...

27 May 2024 8,935 0 View

BD CBA mouse Th cytokine kit vs. Biolegend mouse Th LEGENDplex, which one has better performance?

Hi, Just a quick question for those who have profiled cytokines using sera or cell culturing media supernatant samples. I compared the sensitivity of these two in their manuals and found BD CBA...

14 May 2024 4,596 0 View

How do I get the mathematical model for a flow cytometry assay?

Hi, everyone. I'm tasked with mathematical modeling intracellular cytokines using flow cytometry. Does anyone have a suggestion for the approach I should follow? Maybe there is a technical note...

28 April 2024 4,340 0 View

Does anyone have recommendations which dilution is fine while measuring serum Ang 1, Ang2 and VCAM-1 levels?

Dear colleagues, I will measure serum Ang 1, Ang 2 and VCAM-1 levels by ELISA in patients who were undergone hematopoietic stem cell transplantation. I should find the most suitable dilutions...

21 April 2024 5,222 1 View