Does RAW 264.7 cells express MI like marker CD86?

28 May 2024 1 6K Report

I have come across literature that RAW 264.7 are M1 biased, do they express CD86 without LPS/ IFN stimulation?

Hi Sohini Sen

Some studies suggest RAW 264.7 cells have very low or undetectable levels of CD86 expression under basal conditions, and stimulation by toxins such as LPS, LPS+ATP or H2O2 may be required to upregulate its expression.

Please find the reference attached.

https://pubmed.ncbi.nlm.nih.gov/21777484/

Thanks,

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