what is the reason of difficulty of K562 cell transfection and transduction?
it is assumed that these cells do not do enough endocytosis, which is the pathway used by chemical transfectants and viral transduction.
thank you dear Sandra. is it possible for you to send me the related article?
actually, I do not have really a reference. It's a general assumption from the users' feedbacks we have. I am afraid that these cells are only transfectable via electroporation.
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