Cell membranes have PC, PE, PI and PS as common components. What is the saturated to unsaturated ratio ? I mean such as DPPC: POPC?
Dear Kolattukudy P. Santo ,
The following recent paper provides relevant info when it comes to your question: Weiss-Hersh, K., Garcia, A. L., Marosvölgyi, T., Szklenár, M., Decsi, T., & Rühl, R. (2020). Saturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat. European journal of nutrition, 59(6), 2759-2769. https://link.springer.com/article/10.1007/s00394-019-02121-2
They mention three relevant references:
Andersson A, Nalsen C, Tengblad S, Vessby B (2002) Fatty acid composition of skeletal muscle reflects dietary fat composition in humans. Am J Clin Nutr 76(6):1222–1229. https://doi.org/10.1093/ajcn/76.6.1222
Pacetti D, Gagliardi R, Balzano M, Frega NG, Ojeda ML, Borrero M, Ruiz A, Lucci P (2016) Changes in the fatty acid profile and phospholipid molecular species composition of human erythrocyte membranes after hybrid palm and extra virgin olive oil supplementation. J Agric Food Chem 64(27):5499–5507. https://doi.org/10.1021/acs.jafc.6b01903
Stark KD, Van Elswyk ME, Higgins MR, Weatherford CA, Salem N Jr (2016) Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults. Prog Lipid Res 63:132–152. https://doi.org/10.1016/j.plipres.2016.05.001
Hope these papers will allow you to answer your question.
Best regards.
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