Both are important in their applications.
For e.g., if your analyte is volatile and does not have chromophore in its structure it can be analysed by GC/GCMS. While analyte which is UV active and shows UV absorption in UV/visible range, they can be analysed by HPLC.
It has the principle of parallel operation of HPLC and LC / MS. It is generally preferred for phenolic compounds. You also use it in extracts like hexane and methanol. GC devices are generally preferred for essential oil.
GC-MS will be more useful than HPLC.In GC-MS you will separate and also identify the components from it's m/z(mass/charge) value.NIST-MS library in GCMS will be helpful to search and identify the components.
Do you mean GC-MS and HPLC-MS, or GC-MS and HPLC-UV?
First of all, the analysis depends on the analytes that you want to quantify, if it is thermosensitive, it is better to use HPLC, if not GC technics are more universal.
As for the detection, MS detector is the better solution, to identify and quantify the compounds in a sample.
This is indeed a very effective question. Among the HPLC and GC-MS, indeed the GC-MS is most important. However, the importance depends on the user's need. Sometimes, you need to HPLC to analyze something as all the compounds are not detected using GC-MS, so, in this case you may need to use HPLC. However, using GC-MS, it is possible to quantify at trace level, but using HPLC, it is not possible to to quantify at trace level. Therefore, I think that all the instruments are essential but the importance depends on your desire, actually, what purposes you are interested to use. Thank you for your interest.
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