Most researchers think about the sample size is important.
However, have you ever thought about besides the sample size, there are fatal mistakes in the western medical clinical trials?
Each medicine is under the strict control of toxicity. But a single drug to do the experiment, even no matter how big the sample size is, do not consider two critical factors:
The first is the lifelong use of the heart, liver, kidney long-term damage and thus leads the other organs' functions deviate too.
The second, when more organs have dysfunction, the prescription drug variety increased. It is more than the body can tolerate the toxicity of a single drug. Then, the inevitable organ failure becomes a must happen result!
Or, maybe both of them are equally important?
Dear Frieda,
Whatever the sample size and the duration of the clinical trials, there will always be a lack somewhere. This is why the fourth phase of clinical trials (pharmacovigilance) is carried out after marketing. During this phase all kinds of patients and all the drug-drug interactions can be highlighted.
In preclinical studies, the study of subacute and chronic toxicity evaluating the long-term cumulative effect on the organism is also found, but there is the problem of transposing the animal to humans.
In spite of this, a new drug requires an average of 15 years of research before being commercialized. Unfortunately in some situations (zika, Ebola...) we must find a solution as soon as possible.
In conclusion no type of western medical study is able to answer in a complete way all the questions.
Best regards,
Hocine
Dear Frieda,
This is very important , especially when there are two or more medicine used simultaneously, because there is a lack clinical assay focused in drug interactions. It's correct too that pharmacovigilance system is essential, but I understand there are so many failures and there are a lot of harmful medicine around the world.
sincerely,
Gislei
@Gislei. Thanks for your feedback. I treated severely sick patients. Their situations made me feel sad and I cannot stop to hear or see or get patients asking me to treat them and I refuse them due to I closed my clinic and shifted to teach self-healing to prevent any illness.
Seeing my Mom in Taiwan at the end of the last year., I visited her with tubes ended as I predicted in organ failure. She came to my dreams to ask me to stop the patient's suffering and she left until I promised her to do my best to follow her wish.
@ Dr. Gacem, Thanks for letting me know what is going on. Please let me know where can I follow the fourth phase of clinical trials projects. So, I can share with the other acupuncturists.
For Ebola, SARS, etc. all already had solutions. An acupuncturist wrote a paper about Ebola's Chinese medicine treatment in May 2015. Chinese medicine in the 17th century already knew how to treat the acute, life-threatening infection diseases.
That's why I keep saying here that many nowadays no clue diseases were well solved and documented in ancient Chinese medicine books. The beauty of the Chinese medicine has no organ failure, minimum surgery, amputation, tube be inserted, etc.
Dear Frieda Mah,
I was very happy to hear about your mission. I'm a PhD in pharmacology and I admired the Eastern medicine (like a Chinese Medicine). I understand there are relevant differences between Western and Eastern medicine. Western medicine is focused mainly on the treatment and in scientific knowledge (sometimes strongly associated with economic interests) and Eastern medicine, I think, there is a concern about prophylaxis, prevention and in the focus is holistic and natural. I'm sorry for your mother and I congratulate you on your journey in your land.
Dear Dr. Aragao,
Thanks for your encouraging and kind words. If you have any question, please let me know. I feel so grateful to join this great group that we can share knowledge and make the world to be better.
Chinese medicine development has its unique and superior history that about four thousand and four hundred years ago*, the emperor set government officer to in charge the medical department. The highest officer ought to pass the Emporer's test. Therefore, it plants the concept of finding the economic and humanitarian approach to maintain people's health and happiness. Due to it was an agricultural country, so, how to have healthier people to produce and feed the country is very important.
*http://www2.hkedcity.net/sch_files/a/pts/pts-rick/public_html/new_page_3.htm
Dear Frieda,
The fourth phase of clinical trials is the surveillance by all health professionals as well as patients also after the new drug is commercialized.
For this follow-up, in most countries there is a national pharmacovigilance center (under the aegis of the drug agency) which manages the notifications sent by either health professionals or patients, it groups them, studies them And makes decisions .
For the US you can consult the web site of the FDA (https://www.fda.gov/), for europe: http://ec.europa.eu/health/human-use/pharmacovigilance_en
Http://www.ema.europa.eu/ema/
For UK: https://www.gov.uk/government/organisations/medicines-and-healthcare-products-regulatory-agency
I invite you to read: https://www.gov.uk/government/collections/good-pharmacovigilance-practice-for-medicines-gpvp
Good luck
Hocine
Dear Frieda,
You can visit this website: https://clinicaltrials.gov/
where you can find all clinical trials in progress or completed.
Hope it'll be helpful
Hocine
@Dr. Gacem, Thanks for your info. It takes the time to read. But, I will find time to read. Do you join their jobs?
You're welcome Frieda.
I agree with you regarding the place of traditional medicine as Chinese medicine. I think we should improve them to better use based en evidence and see them as complementary to modern medicine.
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