Saccharomyces cerevisiae is traditionally used for alcohol production. It is highly ethanol tolerant, but, high ethanol concentrations inhibit cell growth and viability. Actually, If you put high ethanol content on this yeast, you can observe fast cell death . During ethanol production by wild type S. cerevisiae in standart conditions, ethanol levels slightly augmented and the yeast to be adopted to this circumstances. The yeast realyses is a transient reprogramming of cellular activities to ensure survival in challenging conditions. They protect essential cell components during recovery. They can change cell sensing capability, signal transduction, transcriptional and posttranscriptional control, protein-targeting, and their own repair functions.