Which one of the drugs (MPTP, Rotenone, Hydroxydopamine) is a better candidate for inducing Parkinson's in Rat? Of course, in a pathway that can increase the Lewy body (α-Synuclein) in the cells.
In your opinion which one the injection methods is best?
1) Deep brain stimulation (DBS)
2) Intravenous injection
or any other methods
Which method is recommended for testing the drug? Oral(by feeding) or Injection?
Thanks
Faris Abachi
Oxotremorin can be injected in dose for rats to give three symptoms will occur: grate one: movement of head.
grate two: head and arms tremor
grate three:head , arms and ledges with salivation
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