Ritter, D., Knebel, J., 2009. Genotoxicity testing in vitro-Development of a higher throughput analysis method based on the comet assay. Toxicol. in Vitro 23, 1570-1575.

Ritter, D., Knebel, J., 2009. Genotoxicity testing in vitro-Development of a higher throughput analysis method based on the comet assay. Toxicol. in Vitro 23, 1570-1575.

Hi Mehran,

We´ve used the "Index of Damage" (ID) to classify the comets of silver stained fish blood cells and crustacean hemocytes. According to Garcia et al. (2004), based on the different degrees of comet tails observed, you establish 5 levels of DNA damage. Then you multiply the number of cells found in each level and determine the ID by summing the level products. Otherwise you can use softwares for image analysis, such as CometScore, CASP, etc.

Sincerely,

Arthur

Hi Dear  Dr Rocha

Thank you so much for your valuable response. That was very helpful. Thank you so much for attached papers, specially for your`s .

Best regards

Mehran 

Dear Dr Dailianis

Thank you so much for your introduced paper. Unfortunately I could`t find the full-text. Would you mind send me the full-text if it can possible?

Best regards

Mehran