Evaluating data stability Following ICH Q1(E) ?

ICH guidline ask for the justification of presentation of new drug substance, to do so we should follow the ICH Q1(E) guideline, This guideline is destinated to evaluate data stability indeed,...

02 March 2018 522 7 View

Why mean responses are used to define surface response?

in the second (optimisation) step of application of design of experiment, we tried to set a model to define most influential factors"we call too surface response methodology" , in parallel, this...

09 October 2017 8,989 2 View

How can we try the system suitability test ?

my question is about the place of system suitability test in developing and validating a New analytical UPLC Chromatography method. its places is considered as a step in the analytical validation...

09 October 2016 283 10 View

Reversed phase liquid chromatography ?

is reversed phase liquid chromatography used only in gradient elution ? what i know we use in reversed phase liquid chromatography (hydrophobic mobile phase)

09 October 2016 160 10 View

What is System suitability test ?

02 March 2016 9,151 3 View

What they means with Concentration of ion-pair reagent?

10 November 2015 3,854 2 View

What is Incurred Samples?

09 October 2015 4,080 1 View

The result of measurement of uncertainty of method should big a small?

in each laboratory analyst are obliged to give a state of uncertainty of their measurement, so in this way the value of uncertainty should be so correct to create a certain reliability between...

08 September 2015 4,880 1 View

How can accuracy profile integrate three parameters of validation as linearity, trueness and precision?

05 June 2015 5,687 3 View

How can we define a acceptance limits in validation studies?

02 March 2015 119 6 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

flexibility of polymers chain

effect of double bond on the flexibility of polymers

07 April 2021 0 0 View

Formulation of polymer color flakes

I am writing to request some information for making polymer color flakes. I would appreciate the help.

17 March 2021 0 0 View

What is the production process of CaFe ferroalloys?

I looking for ferro calcium production process

03 March 2021 1,755 4 View

Is there a powerful system for the security of the systems distributed on IoT systems?

Is there a powerful system for the security of the systems distributed on IoT systems?

02 March 2021 3,858 10 View