12 Questions 16 Answers 0 Followers
Questions related from Yassine Hameda Benchekroun
in pharmaceutical feild : an anlytical method is valid according to the classical approch (descriptive), when the relative coefficient of variation of intermediate precision is less than 3%. in...
01 January 2019 2,202 0 View
ICH guidline ask for the justification of presentation of new drug substance, to do so we should follow the ICH Q1(E) guideline, This guideline is destinated to evaluate data stability indeed,...
03 March 2018 569 7 View
in the second (optimisation) step of application of design of experiment, we tried to set a model to define most influential factors"we call too surface response methodology" , in parallel, this...
10 October 2017 9,033 2 View
my question is about the place of system suitability test in developing and validating a New analytical UPLC Chromatography method. its places is considered as a step in the analytical validation...
10 October 2016 349 10 View
is reversed phase liquid chromatography used only in gradient elution ? what i know we use in reversed phase liquid chromatography (hydrophobic mobile phase)
10 October 2016 268 10 View
to validate any analytical method with the approach of accuracy profile we are obliged to verify the system of suitability test of each method I found in some article that RSD "relative standard...
03 March 2016 9,208 3 View
actually I am working on new project of optimization of new method on UPLC i find this terms in several protocol but i didn't understanding what they means with Concentration of ion-pair reagent?
11 November 2015 3,921 2 View
validation of analytical methods
10 October 2015 4,160 1 View
in each laboratory analyst are obliged to give a state of uncertainty of their measurement, so in this way the value of uncertainty should be so correct to create a certain reliability between...
09 September 2015 4,930 1 View
Validation of analytical method following the total error approach use the accuracy profile, this tool is considered by certain researchers as a statistic which intergrate several parameters of...
06 June 2015 5,736 3 View
we choose the limits of acceptability based on the field in which we work, however, I want to know if it's possible or if there is a relation between limit of acceptability and the 95 % limit of...
03 March 2015 162 6 View
To compute accuracy profile adopted by the SFSTP guide we should use Beta expectation as an interval, so I find another interval which is Beta content in the statistical field. I would like to...
11 November 2014 439 6 View
