To calculate the potency of a powder, you can use the following formula:
Potency of powder (in µg/mg) = Weight of powder (in mg) / (Volume of solvent (in mL) x Concentration of the solution (in mg/mL))
For example, let's say you have 10 mg of powder and you dissolve it in 10 mL of solvent to make a solution with a concentration of 1 mg/mL. If the potency of the powder is 95% (i.e., 950 µg of active ingredient per 1 mg of powder), the potency of the powder can be calculated as follows:
Potency of powder = 10 mg / (10 mL x 1 mg/mL) x (950 µg/1 mg) = 950 µg/mg
So the potency of the powder in this example is 950 µg/mg. This calculation assumes that the entire weight of the powder is composed of the active ingredient, which may not always be the case. In practice, it is important to accurately determine the purity of the powder to obtain an accurate potency calculation.