What is another alternative to Polyvar 2 Microscope with hot plates and polarizer to check for solubility of drug in lipids?

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Hi, I would like to test different disinfectants and its effects on biofilms in microplates, which paper has the best protocols!?

I need to do it only in microplates and read the OD value for the results. I cannot use any other assays except microplate. Please help me with this

07 December 2020 5,698 3 View

What is the acceptable margin error?

The calculated sample size for my study is 324 with 5% margin error. However, only 230 respondents responded the questionnaire completely. In this case, what is the margin error for this actual...

07 July 2020 524 7 View

What is another alternative to Turbisan Lab Expert to check for nano lipid particles stability?

What is another alternative to Turbisan Lab Expert to check for nano lipid carrier's stability?

02 February 2020 9,150 2 View

XPS spectrum of CuO ?

Why the XPS spectrum of CuO doped in WO3 thin film samples show BE peaks of Cu(0) and/or Cu(I) state of copper and also Cu(II) state of copper. What is the reaction mechanism? Here the CuO doped...

26 July 2019 7,634 8 View

Why TDDFT calculation does not match with the experimental UV-Vis spectrum?

I have calculated the structure of a metal(Ag) complex for which the crystal structure data is available with us. The UV-vis spectrum of the complex shows a very strong absorption at ~250 nm and a...

08 October 2018 221 3 View

What is the difference between Factorial ANOVA and Multiple Regression?

I used same variables (3 IVs and 1 DV) to run factorial ANOVA and multiple regression. I expect the similar findings on the linkage between IVs and DV. However, the findings seem not linking each...

30 August 2018 129 13 View

Doubt on microbiological testing ?

I am conducting microbiological testing on QC samples recently. I did a test to get Total bacterial count (TBC) on a sample. And I used pour plate method. I am encountering some errors recently....

15 August 2018 6,673 9 View

Why Factorial ANOVA table called "Test of between Subject Effects" shows no value (-) in F ratio column for interaction between 3 IVs?

I have run Factorial ANOVA to identify main effect and interaction effect between 3 IVs and 1 DV. The output table called "Test of between Subject Effects" shows no value (-) in F ratio column for...

11 August 2018 7,900 3 View

How can I prepare pure NiO oxide from Ni2O3 black nickle oxide??

Is there any simple heat treatment steps? or should I follow any chemical methods?

05 December 2017 2,453 4 View

Correlation based Feature Selection

Can we apply Correlation based Feature Selection algorithm for a dataset containing only numeric value(ie I am using gene data)?

08 February 2017 8,105 8 View

Does any one know how i can prepare liver tissue with transmission electron microscope with good fixation?

i have problem in preparation of liver tissue with bad cell organelles and how i can adjust osmolarity

03 March 2021 8,890 1 View

Is there any test to determine the cardiovascular risk of patients with obesity? from the perspective of obesity?

We found tests to determine cardiovascular risk taking into account lipid profile, blood pressure, age, history of diabetes, other laboratories. But when weight is involved, there is a paradox. I...

02 March 2021 6,036 1 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

Can someone suggest a way to prepare slides to observe under confocal microscope for observing fluorescent tagged proteins??

I am growing the cells on coverslips and transfecting the fluorescent tagged protein directly on them. Then i want to observe these cells under confocal microscope. Currently i am just using...

01 March 2021 6,142 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

Which database would give me this list of chemical components?

Dear colleagues: I would like to know if anyone knows of a database that gives me the parameters pH, K, K, Mg, P, C, N, Zn, Cu, Ni and Cd of common foods. I find a lot of information of proteins,...

26 February 2021 5,525 3 View

How do I choose contrasts in SPM8?

I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...

24 February 2021 1,534 2 View

Do you kow of any database containing data on retention time, log P and polarizability for a large number of molecules?

Hi, I am a chemistry undergraduate doing my dissertation project on HPLC. In my project, I need to predict the HPLC retention time of 20 aromatic molecules, the calibration set. To do this I will...

24 February 2021 2,602 1 View

Which polarizers are usually used to measure the birefringence of zebrafish muscles?

I already found several publications on that topic, however, the specifications for the used filters are often missing. Some more specific information than "fish is placed between to polarizing...

23 February 2021 1,934 1 View