Dear Purva,

You can surely use IONPs in disease models,but i suggest you do a simple bio distribution study via intravenous infusion(tail vein if Rat,mice or Ear lobe vein if Rabbit).You can track the MSCs labelled with IONPs for several days post infusion.

With best regards!!

Thanks charan !

But doing biodistribution studies and inflamation studies will already be an initial part of the study if i work upon some disease models ?

Am I right ?

So what kind of disease models should i focus on......

Thanks for your inputs....indeed.

Looking forward for your reply >>>

Dear Purva,

Yes Bio-distribution and anti inflammatory studies are surely a pre-requisite before going into specific animal studies.You can try the type 2 diabetes,spinal cord injury model,AMI model etc.

Thanks charan !!