What could be the major effective functional group for Fosfomycin to exert its bactericidal action?

Fosfomycin is a bacterial cell wall synthesis inhibitor which can't be grouped into conventional antibiotics i.e. penicillins, cephalosporins, macrolines, quinolones etc. Thus it might be the...

31 December 2017 600 2 View

Is there any relationship between fungal UTI with Bacterial infection in female urinary tract?

Fungal urinary tract infection is very common in women. And many bacteria are also responsible to occurring infection into female urinary tract leading to complicated UTI. Do those infection be...

31 December 2016 8,727 2 View

What are the roles of occupational therapy in modern medicine?

Occupational therapy is gradually spreading out its branches and applications in day to day purposes as well as maintaining a sound job health. I'm much interested to have some distinct and...

10 November 2014 9,409 5 View

Can we think of different options as thyroid suppression?

Many drugs and metal ions in the plasma reduces the incidence of hormonal secretions i.e. Calcium supplements (Ca-citrate) can reduce the parathyroid secretion by 50 % more than the carbonates by...

10 November 2014 1,928 3 View

How can I calculate WOMAC scores using SPSS?

For the interpretation among two or three groups, what tests do I have to perform - can anyone please help me on that regard. I need an independent sample t-test or chi square test?

10 November 2014 4,248 4 View

What segments should be incorporated with a prescription survey?

I've done a prescription survey on gynecological drugs prescribed in Bangladesh. It was a project work. Now I'm developing it to a research article and highly expecting suggestions to make it a...

08 September 2014 9,894 13 View

Proper Public Health Management could have minimized the Ebola virus outbreak - An Open Debate!

"Prevention is better than cure" - the basis on which the science and application of public health stands. But the poor and developing countries have lack in adequate public health measures which...

08 September 2014 4,185 2 View

How can I get the optimum Molecular Weight of the herbal or ayurvedic plant extracts e.g Psyllium husk (Plantago ovata, Plantago ispaghula)?)

Is there any protocol over determining herbal drugs' specification?

07 August 2014 7,005 4 View

Is there any article supporting that calcium orotate doesn't produce kidney stone?

Calcium orotate is the most updated calcium formulation having highest absorption from gut (almost 95%). It is better almost in every cases than calcium carbonate, which in forms oxalate...

06 July 2014 9,613 3 View

How does calcium citrate reduce the risk of oxalate deposition in the kidney?

Calcium Carbonate preparations create calcium oxalate which stores in the kidney and in long run causes the stone formation in kidney. Potassium citrate is used to treat/reduce the oxalate...

06 July 2014 4,300 5 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

I want to performe MALDI-TOF MS for bacterial identification, I would appreciate it if anyone can tell me the matrix solution preparation protocol ?

based on what I've studied on multiple papers, for peptide and protein identification Alpha-cyano-4-hydroxycinnamic acid (CHCA) is an appropriate matrix to use, I also know that the CHCA powder...

26 February 2021 6,799 3 View

How do I choose contrasts in SPM8?

I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...

24 February 2021 1,534 2 View

Universal bacterial primers targeting a mRNA?

Hi, I'm looking for universal primers targeting a bacterial mRNA to quatify bacterial load by qPCR in a complexe mixture (eukaryote and prokaryote RNA). Ribosomal RNA being depleted, I absolutly...

22 February 2021 9,969 3 View

I have a problem with kanamycin - why the kanamycin doesn't affect?

Hi everyone, I need to expression of GFP with pET28 plasmid in E. coli BL21(DE3) plysE. Transformed cells have kanamycin and chloramphenicol resistance. Normally, only transformed cells should...

22 February 2021 4,032 4 View

Does anyone have any ideas why drug-resistant malaria is increasing in Southeast Asia even when those drugs are no longer used?

When dealing with bacterial toxins, there are three varieties of microbes that develop in your petri dish: toxic, resistant, and susceptible. Initially, there are only toxic and vulnerable...

21 February 2021 6,084 5 View

What is the most prevalent drug related problem in the developed countries?

Detecting the drug related problems is an important step in the pharmaceutical care plan

21 February 2021 5,421 3 View

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19 February 2021 8,647 3 View

Could you please share your experience with me on the type of 96 wells plate for MIC determination: Treated Vs Untreated and Round-Vs Flat-bottomed?

I am working on the MIC determination of various antibacterial agents (both water-soluble and- insoluble) against S. aureus, MRSA, and S. pyogenes. Some guidelines recommend using round-bottomed...

17 February 2021 7,029 3 View