Calcium orotate is the most updated calcium formulation having highest absorption from gut (almost 95%). It is better almost in every cases than calcium carbonate, which in forms oxalate containing substances that are responsible for kidney stone, whereas ca-orotate may not involve in kidney stone formation. I'm looking for the supportive papers regarding this.
Orates are known to cause kidney stones. http://informahealthcare.com/doi/abs/10.3109/00365598309179790
http://journals.cambridge.org/action/displayFulltext?type=6&fid=5830648&jid=BJN&volumeId=101&issueId=11&aid=5830644&bodyId=&membershipNumber=&societyETOCSession=&fulltextType=RV&fileId=S0007114509311721
This study says that: Other organic sources, such as calcium ethanolamine phosphate and calcium orotate, are probably bioavailable, but nothing guarantees the safety of the anionic moiety, several grams per d of which would be ingested at the doses prescribed for Ca. A Ca chelate of amino acids, principally in the form of bisglycinate, is often presented as a source of Ca with excellent absorbability, notably due to chelation, which protects it until it reaches the site of absorption. Unfortunately, published studies are too scarce to confirm this.
That's right. It is assumed, but not completely proved yet. As a newer formulation, the less research articles are available.
may be you can start looking in bonding and molecular stability basis.
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