Is there anybody who study Topoisomerase 2 and 4 to give the prosedure about doing this study?
topo 2 Dhifaf Zeki
Dear
Topoisomerases are nuclear enzymes that play essential roles in DNA replication, transcription, chromosome segregation, and recombination.
I recommend you the basic protocol of Nitiss et al. 2013. Curr Protoc Pharmacol. 2012 Jun; CHAPTER: Unit3.3. Check the link below:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397423/
Cordialy
Marius
Thank you very for your attention Mr. Somda
Hi
Some useful information about topo IV itself and its inhibitors are in this research article
https://www.researchgate.net/publication/325066467_New_N_-phenylpyrrolamide_DNA_gyrase_B_inhibitors_Optimisation_of_efficacy_and_antibacterial_activity
Regards
I agree with Naser Jawad Kadhum. good Job.... Naser Jawad Kadhum
Thank you to all dear colleagues
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