There is some drugs, which helps for coronavirus infection - for example chloroquine, tocilizumab, remdesivir, teicoplanin etc. Do you know any other drugs for coronavirus?
Chloroquine (hydroxychloroquine/Plaquenil), a drug used to treat malaria and arthritis, was approved by the US Food and Drug Administration (FDA) to be tested as a treatment for COVID-19.
Favilavir, the first approved coronavirus drug in China
I-Mab Biopharma is developed TJM2, a neutralising antibody, as a treatment for cytokine storm in patients suffering from a severe case of coronavirus infection. The drug targets the human granulocyte-macrophage colony-stimulating factor (GM-CSF), which is responsible for acute and chronic inflammation.
Coronavirus vaccine by Medicago
Medicago is developing drug candidates against COVID-19 after having produced Virus-Like Particles (VLP) of the coronavirus. The company has formed a collaboration with Laval University’s Infectious Disease Research Centre to develop antibodies against SARS-CoV-2
AT-100 by Airway Therapeutics
Airway Therapeutics is exploring its novel human recombinant protein named AT-100 (rhSP-D) as a treatment for coronavirus. The company has announced a filing with the Respiratory Diseases Branch of the National Institutes of Health to evaluate the drug.
TZLS-501 by Tiziana Life Sciences
Tiziana Life Sciences is developing its monoclonal antibody named TZLS-501 for the treatment of COVID-19. TZLS-501 is a human anti-interleukin-6 receptor (IL-6R), which helps in preventing lung damage and elevated levels of IL-6.
OYA1 by OyaGen
OyaGen’s OYA1 has shown strong antiviral efficacy against coronavirus in laboratory essays. It was found to be more effective than chlorpromazine HCl in inhibiting SARS-CoV-2 from replicating in cell culture
BPI-002 by BeyondSpring
BeyondSpring’s BPI-002 is a small molecule agent indicated for treating various infections including COVID-19. It has the ability to activate CD4+ helper T cells and CD8+ cytotoxic T cells and generating an immune response in the body.
Altimmune’s intranasal coronavirus vaccine
An intranasal Covid-19 vaccine is being developed by US-based clinical-stage biopharmaceutical company, Altimmune.
INO-4800 by Inovio Pharmaceuticals and Beijing Advaccine Biotechnology
Inovio Pharmaceuticals has collaborated with Beijing Advaccine Biotechnology Company to advance the development of the former’s vaccine, INO-4800, as a novel coronavirus vaccine. The company has started pre-clinical testing for clinical product manufacturing.
NP-120 (Ifenprodil) by Algernon Pharmaceuticals
Algernon Pharmaceuticals has announced that it is exploring its NP-120 (Ifenprodil) as a potential treatment COVID-19. Ifenprodil is an N-methyl-d-aspartate (NDMA) receptor glutamate receptor antagonist sold under the brand name Cerocal. It has demonstrated efficacy in improving survivability in mice infected with H5N1.
I think minocycline hydrochloride with N.acetylcysteine ,Aspirin and vitamin D, this combination will give the best outcomes, according to my theory MNad therory.
We need collaboration from institution to perform RCT.
I have personally taken Favipiravir and is very effective in low to moderate grade Corona virus infection. I had fever, violent coughing and bit of loose motion.
The antiviral drug remdesivir was FDA approved in October 2020 to treat certain hospitalized patients with COVID-19. And scientists are working hard to develop other effective treatments. Therapies that are under investigation include drugs that have been used to treat autoimmune diseases; additional antiviral drugs, and antibodies from people who have recovered from COVID-19. https://www.health.harvard.edu/diseases-and-conditions/treatments-for-covid-19
The FDA granted EUA to the first treatment, a monoclonal antibody called bamlanivimab made by Eli Lilly, based on an interim analysis of results from a well-designed but small clinical trial. The study looked at 465 non-hospitalized adults with mild to moderate COVID-19 symptoms who were at high risk of severe disease. A placebo was given to 156 of these patients. The remaining patients were given one of three different doses of bamlanivimab. Patients treated with the monoclonal antibody had a reduced risk (3% versus 10%) of being hospitalized or visiting the ER within 28 days after treatment, compared to patients given a placebo. This is a single-dose treatment that must be given intravenously and within 10 days of developing symptoms. https://www.health.harvard.edu/diseases-and-conditions/treatments-for-covid-19
The drug that has been used for several months in many countries in the treatment of people seriously ill with Covid-19 is blood plasma taken from people who have recovered from Covid-19 disease, with no symptoms or mild disease. However, currently (January 2021), the greatest hopes are placed on vaccines against Coronavirus administered to people.