Hi Ajay,

I've been using two great tools for GPCR, available as standalone for downloading and as web servers, too. Check them out:

Constrained Consensus TOPology prediction server:

http://cctop.enzim.ttk.mta.hu

http://cctop.enzim.ttk.mta.hu/?_=//documents/standalone.html

and HMMTOP (earlier work from the same group):

http://www.enzim.hu/hmmtop/index.php

Best,

Karoly

Hi Karoly

Thanks for sharing the links.

I am just curious about one thing you might have answer to:

as when Pymol reads the PDB file - how does it infer from xyz coordinates (from PDB file) to show protein in different tertiary structures- say helices - does it follow some sort of h-bonding pattern i+4 for helices ?

Ajay, sorry, but I'm an experimental guy, used pymol occasionally for presentation of structures, so I can't answer this question. Best: Karoly