splicing of insulin genes?

07 November 2013 1 6K Report

Splicing an insulin gene results in two isoforms of the insulin receptor, A and B, where A implicates a mitogenic effect and B a metabolic effect. But for the mitogenic effect, IGF-1R is present and also implicates a similar function to Insulin receptor A.

Why is this splicing happening in the insulin gene, when we have IGF-1R for a similar function?

Tausif Alam

Redundancy assures survival!

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